Radiology and imaging serve as the eyes of modern medicine, allowing doctors to peer inside the human body without making a single incision. This rapidly evolving field uses technologies like X-rays, MRI scans, and ultrasound to detect diseases, guide treatments, and monitor patient recovery. As new research emerges, these visual tools become increasingly sophisticated, offering deeper insights into conditions ranging from broken bones to complex neurological disorders.

At Gist.Science, we bridge the gap between raw scientific data and public understanding by processing every new preprint in this category from medRxiv. Our team translates these complex studies into both plain-language overviews and detailed technical summaries, ensuring that breakthroughs in medical imaging are accessible to everyone, from students to specialists. Below are the latest papers in radiology and imaging, ready for you to explore.

📄 radiology and imaging

Association of plasma biomarkers with longitudinal change in age- and Alzheimer's disease-related brain atrophy patterns

In cognitively unimpaired individuals from the Baltimore Longitudinal Study of Aging, plasma p-tau217 demonstrated the strongest association with both subsequent Alzheimer's disease-related dementia and longitudinal changes in AD-specific brain atrophy patterns compared to other plasma biomarkers.

Bilgel, M., Shah, I., Cooper, J., An, Y., Walker, K. A., Ho, S. G., Moghekar, A. R., Yang, Z., Erus, G., Davatzikos, C. (…)2026-09-17
📄 radiology and imaging

Hyperspectral imaging in the emergency department to characterize lower leg edema

This study demonstrates that visible/near-infrared hyperspectral imaging, particularly when analyzed using full-spectrum machine learning algorithms, can accurately and rapidly classify cellulitis, non-cellulitis edema, and healthy lower-leg tissue in emergency department patients across diverse skin pigmentation types.

Kasi, K., May, C., Gallegos, H., Kobayashi, L., Conway, B. R., Pare, J. R.2026-09-16
📄 radiology and imaging

Liver functional radiomics of gadoxetic acid-enhanced magnetic resonance imaging: A proof-of-concept study

This proof-of-concept study identified a set of reproducible and repeatable radiomics features from gadoxetic acid-enhanced MRI that significantly correlate with quantitative liver function indices, establishing a foundation for future liver function-related radiomics research.

Wang, Q., Grigoriadis, A., Gilg, S., Tzortzakakis, A., Sparrelid, E., Brismar, T. B.2026-09-14
📄 radiology and imaging

Diameter measurement of tubular structures on CT angiography, 3D rotational angiography, and 2D digital subtraction angiography against caliper ground truth: A phantom study of surrogates for intracranial vessels.

This phantom study evaluates the accuracy of CTA, 3DRA, and 2D DSA in measuring intracranial vessel diameters against physical ground truth, revealing that while all modalities generally measure within 0.5 mm of true dimensions, they exhibit consistent biases that vary by vessel size, contrast concentration, and detection algorithm, with maximum-gradient edge detection proving superior to FWHM and fixed-HU methods.

Alexander, M., Settecase, F.2026-09-08
📄 radiology and imaging

LDCT-to-SDCT as a Bridge Problem: Single-Step Residual Endpoint Flow Matching for Real-Time Denoising

This paper introduces Residual Endpoint Flow Matching (REFM), a single-step deep learning method that leverages the inherent anatomical similarity between low-dose and standard-dose CT images to achieve real-time, high-quality denoising comparable to iterative diffusion models while drastically reducing computational costs.

dela Sotta, T., Saavedra, J. M., Chang, V., Xavier, A., Henriquez, H., Orellana, Y., Curimil, J.2026-08-31
📄 radiology and imaging

Adaptive Post-Processing Recovers Most of the Gap to nnU-Net v2 in Head and Neck GTV Segmentation: A Paired Three-Arm HECKTOR 2025 Benchmark

This HECKTOR 2025 benchmark demonstrates that while adaptive post-processing significantly narrows the performance gap between a lightweight MiniUNet3D and the larger nnU-Net v2 for head and neck tumor segmentation, it fails to fully eliminate differences in nodal disease accuracy or prevent a higher rate of catastrophic failures on small primary tumors.

Oyarzun Silva, R., Hernandez Hernandez, P.2026-08-31
📄 radiology and imaging

Image transmission through a multimode fibre in reflection mode with physics-guided deep learning towards ultrathin endoscopy

This paper presents a physics-guided deep learning framework that combines a reflected real-valued intensity transmission matrix with image restoration networks to enable single-shot, phase-retrieval-free image recovery through multimode fibres in reflection mode, significantly improving image quality and generalizability for ultrathin endoscopy.

Ye, Z., He, F., Zhao, T., Xia, W.2026-08-31
📄 radiology and imaging

Label-Free Threshold Selection for Out-of-Distribution Detection in Liver CT Segmentation

This paper proposes a label-free framework for calibrating out-of-distribution detection thresholds in liver CT segmentation by fitting a log-t distribution to pairwise surface DSC scores, enabling statistically principled failure risk categorization without requiring expert-labeled failure data.

Nielsen, M., Castelo, A., Altaie, M., Bennett, J., Anthony, A., Siddiqi, N. S., Gupta, A. C., Brock, K. K., Woodland, M.2026-08-24